Interstitial Cystitis

Millions of patients suffer from interstitial cystitis/painful bladder syndrome. This severe and debilitating condition has historically been confused with other bladder pathology which must be ruled out, making IC difficult to diagnose. Currently, IC/PBS is defined as “an unpleasant sensation (pain, pressure, discomfort) perceived to be related to the urinary bladder... Read More
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Peyronies Disease

Peyronies Disease has been described by experts as a physically and psychologically devastating problem manifested by a fibrous inelastic scar of the fibrous chambers of the penis known as the tunica albuginea. The scarring (known as “peyronies plaques”) can cause pain, bending, narrowing, hinging and shortening of the penis in the erect state... Read More
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Erectile Dysfunction

Erectile Dysfunction is defined as the inability to achieve or sustain an erection suitable for sexual intercourse. ED affects up to one third of men of men throughout their lives and has a substantial negative impact on intimate relationships, quality of life and self-esteem. Causes are multifactorial but can be related to loss of testosterone, surgical damage to the penile nerves, medications, or other medical illnesses... Read More
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Male Incontinence

In America alone, more than three million men are affected by loss of bladder control, a medical condition known as urinary incontinence. This problem has a great impact on health and quality of life for those who suffer with it. Male urinary incontinence is usually caused by a damaged sphincter, the circular muscle that controls the flow of urine out of the bladder... Read More
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Urology Library

Mesenchymal stem cells and immunomodulation: toward new immunosuppressive strategies for the treatment of autoimmune diseases?

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Rev Med Interne. 2009 Mar;30(3):287-99. Epub 2008 Oct 17. Mesenchymal stem cells and immunomodulation: toward new immunosuppressive strategies for the treatment of autoimmune diseases? [Article in French] Larghero J, Vija L, Lecourt S, Michel L, Verrecchia F, Farge D. Source Unité de thérapie cellulaire, Hôpital Saint-Louis, AP-HP, Paris, France. Abstract Mesenchymal stem cells (MSC) represent […]

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Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks.

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Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks. Tyndall A, Uccelli A. Source Department of Rheumatology, University of Basel, University Rheumatology Clinic, Basel, Switzerland. alan.tyndall@fps-basel.ch Abstract MSCs, otherwise known as multipotent mesenchymal stromal cells, are being examined for the treatment of autoimmune disease (AD) on the basis of their in vitro […]

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Adult stem cells in the treatment of autoimmune diseases.

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Rheumatology (Oxford). 2006 Oct;45(10):1187-93 Adult stem cells in the treatment of autoimmune diseases. Authors: van Laar JM, Tyndall A During the past 10 yrs, over 700 patients suffering from severe autoimmune disease (AD) have received an autologous haematopoietic stem cell transplant as treatment of their disorder with durable remission being obtained in around one-third. The […]

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Autologous stem cell transplantation for severe autoimmune diseases: a 10-year experience.

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Ann N Y Acad Sci. 2007 Sep;1110:455-64 Autologous stem cell transplantation for severe autoimmune diseases: a 10-year experience. Authors: Gualandi F, Bruno B, Van Lint MT, Luchetti S, Uccelli A, Capello E, Mancardi GL, Bacigalupo A, Marmont A The first autologous hematopoietic stem cell transplantation in Europe for a patient with severe refractory systemic lupus […]

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Immunoregulatory effect of bone marrow mesenchymal stem cells on regulatory T cells in patients with systemic lupus erythematosis

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Zhonghua Nei Ke Za Zhi. 2007 Dec;46(12):1018-21 Immunoregulatory effect of bone marrow mesenchymal stem cells on regulatory T cells in patients with systemic lupus erythematosis  Authors: Sun Y, Zhang FS, Zhang ZY OBJECTIVE: To study the in vitro modulation of autogeneic and allogenic regulatory T lymphocytes proliferation by bone marrow mesenchymal stem cells (MSCs) in […]

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Hematopoietic stem cell transplantation in autoimmune diseases

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Medicina (B Aires). 2008;68(2):153-63 Hematopoietic stem cell transplantation in autoimmune diseases Authors: Albarracín F, López Meiller MJ, Naswetter G, Longoni H Transplantation of hematopoietic stem cells, which are capable of self renewal and reconstitution of all types of blood cells, can be a treatment for numerous potential lethal diseases, including leukemias and lymphomas. It may […]

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Autoimmune disease: is it a disorder of the microenvironment?

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Immunol Res. 2008;41(1):79-86 Autoimmune disease: is it a disorder of the microenvironment? Authors: El-Badri NS, Hakki A, Ferrari A, Shamekh R, Good RA Systemic lupus erythematosus (SLE) is a common systemic autoimmune disease that involves several vital organs including the cardiovascular system, joints, and kidneys. The pathology is characterized by accumulation of autoreactive lymphocytes that […]

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Cell-assisted lipotransfer for facial lipoatrophy: efficacy of clinical use of adipose-derived stem cells.

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Cell-assisted lipotransfer for facial lipoatrophy: efficacy of clinical use of adipose-derived stem cells. Yoshimura K, Sato K, Aoi N, Kurita M, Inoue K, Suga H, Eto H, Kato H, Hirohi T, Harii K. Source Department of Plastic Surgery, University of Tokyo School of Medicine, Tokyo, Japan. yoshimura-pla@h.u-tokyo.ac.jp Abstract BACKGROUND: Lipoinjection is a promising treatment, but […]

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Transplantation of human bone marrow mesenchymal stem cell ameliorates the autoimmune pathogenesis in MRL/lpr mice.

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Cell Mol Immunol. 2008 Dec;5(6):417-24. Transplantation of human bone marrow mesenchymal stem cell ameliorates the autoimmune pathogenesis in MRL/lpr mice. Zhou K, Zhang H, Jin O, Feng X, Yao G, Hou Y, Sun L. Source Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Jiangsu, China. Abstract Recent evidence […]

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Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks.

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Bone Marrow Transplant. 2009 Jun;43(11):821-8. Epub 2009 Mar 23. Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks. Tyndall A, Uccelli A. Source Department of Rheumatology, University of Basel, University Rheumatology Clinic, Basel, Switzerland. alan.tyndall@fps-basel.ch Abstract MSCs, otherwise known as multipotent mesenchymal stromal cells, are being examined for the treatment of autoimmune […]

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