Scleroderma

Scleroderma also known as systemic sclerosis, is a systemic autoimmune disease characterized by damage to endothelial and smooth muscle cells of the small arteries. Replacement with fibrous material results, and there is an influx of inflammatory cells. Primarily affects skin and joints but can affect the heart and lungs, and digestive tract... Read More
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Auto-Immune Neuropathy and CIDP

CIDP also known as chronic inflammatory demyelinating polyneuropathy is an auto-immune disease of the nervous system characterized by progressive weakness and impaired sensory function in the legs and arms. CIDP is closely related to Guillan-Barre Disease. Treatment for CIDP includes steroids and immunosuppressant drugs... Read More
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Myasthenia Gravis

Myasthenia gravis is an autoimmune neuromuscular disease leading to fluctuating muscle weakness and fatigability. It is an autoimmune disorder, in which weakness is caused by circulating antibodies that inhibit the excitatory effects of the neurotransmitter acetylcholine on neuromuscular junctions. Muscular fatigue is often seen and MG is associated with ocular problems, and speech, swallowing, and breathing can be affected... Read More
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Rheumatoid Arthritis

Rheumatoid arthritis is an autoimmune disease common in middle age, especially in women. The disease affects peripheral joints, including the wrists, feet, ankles, and knees. The cause is unknown and eyes and skin also can be involved. Early aggressive therapy with immunosuppressive drugs and anti-inflammatories appears to delay joint destruction... Read More
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Crohns Disease

The incidence and prevalence of Crohn’s disease and ulcerative colitis, the two major forms of inflammatory bowel disease (IBD), are rising. According to some estimates >1 million new cases of IBD arise in the United States annually. The conventional therapies available for IBD range from anti-inflammatory drugs to immunosuppressive agents, but these therapies generally fail to achieve satisfactory results due to their side effects... Read More
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Auto-Immune Hepatitis

Auto-immune hepatitis is an inflammatory auto-immune disease of the liver. It often occurs with other auto-immune conditions such as scleroderma, lupus, Crohn’s, and Graves thyroid disease. Patients experience fatigue, loss of appetite, itching, and abdominal distension. Treatment with corticosteroids is the standard... Read More
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Relapsing Polychondritis

Relapsing Polychondritis is an auto-immune condition characterized by the body attacking its own cartilage. Polychondritis patients suffer from recurrent relapsing episodes of painful cartilage inflammation. Susceptible areas include ears, nasopharynx, heart valves, and blood vessels. As stated in Annals of Internal Medicine, Relapsing Polychondritis…can be life-threatening and debilitating... Read More
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Alopecia Areata

Alopecia Areata is a genetically related auto-immune condition in which the body attacks its own hair follicles resulting in small bald patches. It can involve the entire scalp (totalis) or the entire body (universalis). Sometimes patients spontaneously improve and others continue to worsen. Steroid therapy and topical immune-suppressants are frequently used for treatment. There are ongoing clinical trials using growth factor inhibitors to mitigate the hair loss... Read More
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Lupus

Systemic Lupus Erythematosus, considered a collection of diseases, is an auto-immune disorder in which the immune system attacks healthy tissues, especially in the joints (especially fingers, wrists, hands, and knees). Patients often develop fatigue, rash, and swollen lymph nodes, but many body parts can be affected... Read More
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Urology Library

Stem Cell Therapy: Hope or Hoax?

Filed under Hair Restoration Library, Neurology Library, Rheumatoid Arthritis Library, Stem Cell Research Studies

Chicago Stem Cell Treatment Center, an affiliate of Stem Cell Surgical Network features stem cell therapy insight on My Fox LA. Click here for the video: Stem Cell Therapy: Hope or Hoax **********************************************************************************************************************************

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Stem cells and alopecia: a review of pathogenesis.

Filed under Lupus Library

Br J Dermatol. 2012a Sep;167(3):479-84. doi: 10.1111/j.1365-2133.2012.11018.x. Epub 2012 Aug 8. Stem cells and alopecia: a review of pathogenesis. Al-Refu K. Source Faculty of Medicine, Internal Medicine Department, Mu’tah University, PO Box 5, Karak, Mu’tah 61710, Jordan. Abstract Recent work has focused on the hair follicle as the main source of multipotent stem cells in […]

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Therapeutic Effects of Umbilical Cord Blood-Derived Mesenchymal Stem Cell Transplantation in Experimental Lupus Nephritis.

Filed under Lupus Library

Cell Transplant. 2010 Aug 18; Therapeutic Effects of Umbilical Cord Blood-Derived Mesenchymal Stem Cell Transplantation in Experimental Lupus Nephritis. Authors: Chang JW, Hung SP, Wu HH, Wu WM, Yang AH, Tsai HL, Yang LY, Lee OK Msenchymal stem cells (MSCs) have been shown to possess immuno-modulatory properties. Systemic lupus erythematosus is an autoimmune disease which […]

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ReMobilization, harvesting and selection of peripheral blood stem cells in patients with autoimmune diseases undergoing autologous hematopoietic stem cell transplantation.

Filed under Lupus Library

Bone Marrow Transplant. 2007 Mar;39(6):317-29 ReMobilization, harvesting and selection of peripheral blood stem cells in patients with autoimmune diseases undergoing autologous hematopoietic stem cell transplantation. Authors: Statkute L, Verda L, Oyama Y, Traynor A, Villa M, Shook T, Clifton R, Jovanovic B, Satkus J, Loh Y, Quigley K, Yaung K, Gonda E, Krosnjar N, Spahovic […]

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Cell therapy for autoimmune diseases.

Filed under Lupus Library

Arthritis Res Ther. 2007;9(2):206 Cell therapy for autoimmune diseases. Authors: Dazzi F, van Laar JM, Cope A, Tyndall A Cell therapy, pioneered for the treatment of malignancies in the form of bone marrow transplantation, has subsequently been tested and successfully employed in autoimmune diseases. Autologous haemopoietic stem cell transplantation (HSCT) has become a curative option […]

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Haemopoietic stem cell transplantation–an evolving treatment for severe autoimmune and inflammatory diseases in rheumatology, neurology and gastroenterology.

Filed under Lupus Library

Hematology. 2007 Jun;12(3):179-91 Haemopoietic stem cell transplantation–an evolving treatment for severe autoimmune and inflammatory diseases in rheumatology, neurology and gastroenterology. Authors: Kapoor S, Wilson AG, Sharrack B, Lobo A, Akil M, Sun L, Dalley CD, Snowden JA The concept of haemopoietic stem cell transplantation (HSCT) to treat severe autoimmune diseases has been around for several […]

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The use of stem cells for the treatment of autoimmune diseases.

Filed under Lupus Library

Braz J Med Biol Res. 2007 Dec;40(12):1579-97 The use of stem cells for the treatment of autoimmune diseases. Authors: Rosa SB, Voltarelli JC, Chies JA, Pranke P Autoimmune diseases constitute a heterogeneous group of conditions commonly treated with anti-inflammatory, immunosuppressant and immunomodulating drugs, with satisfactory results in most cases. Nevertheless, some patients become resistant to […]

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Autologous hematopoietic stem cell transplantation for autoimmune diseases: an observational study on 12 years’ experience from the European Group for Blood and Marrow Transplantation Working Party on Autoimmune Diseases.

Filed under Lupus Library

Haematologica. 2010 Feb;95(2):284-92 Autologous hematopoietic stem cell transplantation for autoimmune diseases: an observational study on 12 years’ experience from the European Group for Blood and Marrow Transplantation Working Party on Autoimmune Diseases. Authors: Farge D, Labopin M, Tyndall A, Fassas A, Mancardi GL, Van Laar J, Ouyang J, Kozak T, Moore J, Kötter I, Chesnel […]

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Technology Insight: hematopoietic stem cell transplantation for systemic rheumatic disease.

Filed under Lupus Library

Nat Clin Pract Rheumatol. 2008 Apr;4(4):184-91 Technology Insight: hematopoietic stem cell transplantation for systemic rheumatic disease. Authors: Nikolov NP, Pavletic SZ Hematopoietic stem cells (HSCs) have the capacity for self-renewal and the potential to differentiate into all types of hematopoietic and immune system cells. These features have been successfully used to treat a multitude of […]

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Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes.

Filed under Lupus Library

Diabetes Metab. 2009 Apr;35(2):85-93. Epub 2009 Feb 20. Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes. Vija L, Farge D, Gautier JF, Vexiau P, Dumitrache C, Bourgarit A, Verrecchia F, Larghero J. Source Inserm U697, Paris, France. Abstract Mesenchymal stem cells (MSCs) are multipotent non-haematopoietic progenitor cells that are being explored as […]

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